Invention Grant
- Patent Title: Drug active in neuropathic pain
- Patent Title (中): 药物活性在神经性疼痛
-
Application No.: US12738499Application Date: 2008-11-06
-
Publication No.: US08455519B2Publication Date: 2013-06-04
- Inventor: Maria Alessandra Alisi , Nicola Cazzolla , Guido Furlotti , Angelo Guglielmotti , Lorenzo Polenzani
- Applicant: Maria Alessandra Alisi , Nicola Cazzolla , Guido Furlotti , Angelo Guglielmotti , Lorenzo Polenzani
- Applicant Address: IT Rome
- Assignee: Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A.
- Current Assignee: Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A.
- Current Assignee Address: IT Rome
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: EP07425709 20071112
- International Application: PCT/EP2008/065081 WO 20081106
- International Announcement: WO2009/062883 WO 20090522
- Main IPC: C07D211/32
- IPC: C07D211/32 ; A61K31/445

Abstract:
The present invention relates to a compound of formula (I): in which: R is a linear or branched alkyl group containing between 1 and 3 carbon atoms, Y is CH or N, and p is an integer between 0 and 3 and preferably 0 and 1, and salts thereof, either acid-addition salts with a pharmaceutically acceptable organic or mineral acid, or base-addition salts with a pharmaceutically acceptable organic or mineral base. The invention also relates to a process for preparing the compound of formula (I), and to a pharmaceutical composition comprising it. The invention also relates to the use of an indazole for preparing a pharmaceutical composition that is active in the treatment of neuropathic pain.
Public/Granted literature
- US20100215742A1 DRUG ACTIVE IN NEUROPATHIC PAIN Public/Granted day:2010-08-26
Information query