Invention Grant
US08455520B2 Soluble epoxide hydrolase inhibitors, compositions containing such compounds and methods of treatment
有权
可溶性环氧化物水解酶抑制剂，含有这些化合物的组合物和治疗方法
- Patent Title: Soluble epoxide hydrolase inhibitors, compositions containing such compounds and methods of treatment
- Patent Title (中): 可溶性环氧化物水解酶抑制剂，含有这些化合物的组合物和治疗方法
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Application No.: US12668494Application Date: 2008-07-11
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Publication No.: US08455520B2Publication Date: 2013-06-04
- Inventor: Steven L. Colletti , Hong Shen , Fa-Xiang Ding
- Applicant: Steven L. Colletti , Hong Shen , Fa-Xiang Ding
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Anna L. Cocuzzo; Richard C. Billups; John C. Todaro
- International Application: PCT/US2008/008693 WO 20080711
- International Announcement: WO2009/011872 WO 20090122
- Main IPC: A61K31/4985
- IPC: A61K31/4985 ; A61K31/4725 ; A61K31/4545 ; A61K31/454 ; A61K31/451 ; A61K31/445 ; C07D417/12 ; C07D413/12 ; C07D413/04 ; C07D401/12 ; C07D401/06 ; C07D401/04 ; C07D211/60 ; C07D211/56 ; C07D211/62 ; C07D211/34 ; C07D211/22 ; C07D211/16
Abstract:
Compounds of the Formula: (I) as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating hypertension, diabetes, inflammation, atherosclerosis, pain, and the like are disclosed. Pharmaceutical compositions and methods of use are also included.
Public/Granted literature
- US20100197691A1 SOLUBLE EPOXIDE HYDROLASE INHIBITORS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT Public/Granted day:2010-08-05
Information query
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