Invention Grant
- Patent Title: Imidazole derivatives useful as inhibitors of FAAH
- Patent Title (中): 可用作FAAH抑制剂的咪唑衍生物
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Application No.: US12996429Application Date: 2009-06-04
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Publication No.: US08455528B2Publication Date: 2013-06-04
- Inventor: Linus S. Lin , Marc D. Chioda , Ping Liu , Ravi P. Nargund
- Applicant: Linus S. Lin , Marc D. Chioda , Ping Liu , Ravi P. Nargund
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Maria V. Marucci
- International Application: PCT/US2009/046241 WO 20090604
- International Announcement: WO2009/152025 WO 20091217
- Main IPC: A61K31/4174
- IPC: A61K31/4174 ; A61K31/4178 ; C07D233/84
Abstract:
The present invention is directed to certain imidazole derivatives which are useful as inhibitors of Fatty Acid Amide Hydrolase (FAAH). The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including osteoarthritis, rheumatoid arthritis, diabetic neuropathy, postherpetic neuralgia, skeletomuscular pain, and fibromyalgia, as well as acute pain, migraine, sleep disorder, Alzeimer Disease, and Parkinson's Disease.
Public/Granted literature
- US20110269769A1 IMIDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH Public/Granted day:2011-11-03
Information query
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