Invention Grant
- Patent Title: Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
-
Application No.: US13390538Application Date: 2010-08-23
-
Publication No.: US08455533B2Publication Date: 2013-06-04
- Inventor: Tesfaye Biftu , Ping Chen , Danqing Feng , Xiaoxia Qian
- Applicant: Tesfaye Biftu , Ping Chen , Danqing Feng , Xiaoxia Qian
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Janet E. Fair; John C. Todaro
- International Application: PCT/US2010/046270 WO 20100823
- International Announcement: WO2011/028455 WO 20110310
- Main IPC: A61K31/4162
- IPC: A61K31/4162 ; C07D231/00
Abstract:
The present invention is directed to novel substituted aminotetrahydropyrans of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Public/Granted literature
- US20120149734A1 AMINOTETRAHYDROPYRANS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES Public/Granted day:2012-06-14
Information query
IPC分类:
