Invention Grant
- Patent Title: Heteroaryl dihydroindolones as kinase inhibitors
- Patent Title (中): 杂芳基二氢吲哚酮作为激酶抑制剂
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Application No.: US13150543Application Date: 2011-06-01
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Publication No.: US08455535B2Publication Date: 2013-06-04
- Inventor: Sougato Boral , Xialing Guo , Shimiao Wang , Julie A. Wurster , Thomas C. Malone
- Applicant: Sougato Boral , Xialing Guo , Shimiao Wang , Julie A. Wurster , Thomas C. Malone
- Applicant Address: US CA Irvine
- Assignee: Allergan, Inc.
- Current Assignee: Allergan, Inc.
- Current Assignee Address: US CA Irvine
- Agent Krishna G. Banerjee
- Main IPC: A61K31/4015
- IPC: A61K31/4015 ; C07D209/34
Abstract:
The present invention provides a compound represented by the formula: wherein ring systems A and B, and the variables R1, b, R6, Y, Z, X, R and a are defined in the specification. The compounds of the present invention may be used in a method for treating diseases related to unregulated tyrosine kinase signal transduction, such as cancer, blood vessel proliferative disorders, fibrotic disorders, mesangial cell proliferative disorders, and metabolic diseases.
Public/Granted literature
- US20110257238A1 Heteroaryl Dihydroindolones as Kinase Inhibitors Public/Granted day:2011-10-20
Information query
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