Invention Grant
US08455648B2 1-(7-(hexahydropyrrolo [3,4-c] pyrrol-2 (1H)-yl) quinolin-4-yl) -3- (pyrazin-2-yl) urea derivatives and related compounds as glycogen synthase kinase 3 (GSK-3)
有权
1-(7-(六氢吡咯并[3,4-c]吡咯-2(1H) - 基)喹啉-4-基)-3-(吡嗪-2-基)脲衍生物和相关化合物作为糖原合酶激酶3 GSK-3)
- Patent Title: 1-(7-(hexahydropyrrolo [3,4-c] pyrrol-2 (1H)-yl) quinolin-4-yl) -3- (pyrazin-2-yl) urea derivatives and related compounds as glycogen synthase kinase 3 (GSK-3)
- Patent Title (中): 1-(7-(六氢吡咯并[3,4-c]吡咯-2(1H) - 基)喹啉-4-基)-3-(吡嗪-2-基)脲衍生物和相关化合物作为糖原合酶激酶3 GSK-3)
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Application No.: US12988833Application Date: 2009-04-24
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Publication No.: US08455648B2Publication Date: 2013-06-04
- Inventor: Sean Colm Turner , Margaretha Henrica Maria Bakker , Wilfried Hornberger
- Applicant: Sean Colm Turner , Margaretha Henrica Maria Bakker , Wilfried Hornberger
- Applicant Address: DE Wiesbaden
- Assignee: Abbott GmbH & Co. KG
- Current Assignee: Abbott GmbH & Co. KG
- Current Assignee Address: DE Wiesbaden
- Agency: Michael Best & Friedrich LLP
- Agent Lisa V. Mueller
- Priority: EP08155133 20080424
- International Application: PCT/EP2009/054987 WO 20090424
- International Announcement: WO2009/130317 WO 20091029
- Main IPC: C07D215/38
- IPC: C07D215/38
![1-(7-(hexahydropyrrolo [3,4-c] pyrrol-2 (1H)-yl) quinolin-4-yl) -3- (pyrazin-2-yl) urea derivatives and related compounds as glycogen synthase kinase 3 (GSK-3)](/abs-image/US/2013/06/04/US08455648B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to novel heterocyclic compounds which are useful for inhibiting glycogen synthase kinase 3 (GSK-3), methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
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