A panel adjustment method is executed on a host to adjust settings of a panel connected to the host through a serial bus. The method determines whether the panel is supported by the host. When the panel is supported by the host, the settings of the panel is read from a database of the host to accordingly set the panel. It is further determined whether the panel is correctly set or not. When the panel is correctly set, it is further determined whether the panel is of a frame buffer mode or not. When the panel is of a frame buffer mode, it is determined whether a header file generation is required or not. When the header file generation is required, the settings and a panel name are included in an include file. The include file is compiled to thereby generate a binary file which is loaded into the panel.