An isolated switched mode power supply (SMPS) is disclosed. The SMPS comprises a switching controller to generate start-up and operational switching control signals. The SMPS further includes a transformer, having a primary winding, and a full-bridge drive circuit to drive the primary winding. The full-bridge drive circuit comprises a first switching element, a boot-strap dnving circuit, and a second switching element. The switching controller is further used to start up isolated SMPS by determining a duty cycle for operational control signals and generating the start-up switching control signals.