A transmitter includes a resistor, a protection unit, and a transmission unit. The resistor control unit controls a connection of a termination resistor between first and second transmission lines. The protection unit reduces first and second voltages, respectively, from the first and second transmission lines during a power-down mode. The transmission unit receives the dropped first and second voltages during the power-down mode and transmits first and second signals through the protection unit during a power-on mode. The resistor control unit connects the termination resistor to the first and second transmission lines when a transmission rate of the first and second signals is equal to or greater than a predetermined value. The resistor control unit is disconnected from at least one of the first and second transmission lines when the transmission rate is less than the predetermined value.