A device is adapted for use in a body area network capable of low power communications wherein a number of piconets can operate within close proximity. The device is configured to couple to a plurality of secondary devices in a piconet. The device uses an interference mitigation technique to enable the devices in the piconet to use the same frequency and same time as a number of adjacent piconets located in close proximity to the piconet. The interference mitigation technique is at least one of a low duty cycling operation; and a preamble sequence designed to operate under interference.