A circuit configuration for serial communication includes a first half for receiving and emitting sensing and/or actuating signals; a second half for receiving and emitting sensing and/or actuating signals, a two wire connecting line, which connects bidirectionally the first half and the second half of the circuit configuration; and a wake up switching device for waking up the first and second halves of the circuit configuration out of their standby mode without quiescent current. Independently of the switching state of the wake up switching device, a high level state at the output of a second low pass filter device holds a first switching device in its closing state, and a high level state at the output of a first low pass filter device holds a second switching device in its closing state, as a result of which a self-holding of the supply voltage is guaranteed.