A method of optimizing an autoclave volume utilization includes, in an exemplary embodiment, determining process parameters of an autoclave; modeling an autoclave configuration to determine airflow patterns in the autoclave, temperature variation throughout the autoclave, and the distribution of turbulent intensity in the autoclave; and modifying the autoclave configuration with hardware changes to the autoclave to alter the airflow patterns in the autoclave. The method also includes modeling the modified autoclave configuration to determine modified airflow patterns in the autoclave, modified temperature variation throughout the autoclave, and the modified distribution of turbulent intensity in the autoclave; and modeling the modified autoclave configuration with parts to be cured in the modified autoclave configuration to determine an arrangement of parts that maximizes the number of parts in the autoclave that meet predetermined cured properties of the parts.