Systems and methods for secure access and utilization of sensitive data such as credit card numbers, Social Security Numbers, personal identifying information, etc. A tokenizing strategy component provides for creating, managing, and storing tokenization strategies on behalf of a plurality of users. A data tokenizing component is operative to (a) receive an input data string of sensitive data from a user, (b) apply a selected tokenization strategy to the input data string to generate a tokenized data string, and (c) provide the tokenized data string for storage in association with the input data string. A secure server including a secure database stores the tokenized data string and the input data string in a corresponding mapped relationship. A security component controls access to and retrieval of the tokenized data string and to the input data string in accordance with predetermined security requirements of the users.