Invention Grant
US08460711B2 Poly(citric acid) functionalized carbon nanotube drug delivery system
有权
聚(柠檬酸)官能化碳纳米管药物递送系统
- Patent Title: Poly(citric acid) functionalized carbon nanotube drug delivery system
- Patent Title (中): 聚(柠檬酸)官能化碳纳米管药物递送系统
-
Application No.: US12870943Application Date: 2010-08-30
-
Publication No.: US08460711B2Publication Date: 2013-06-11
- Inventor: Fatemeh Atyabi , Mohsen Adeli , Zahra Sobhani , Rassoul Dinarvand , Mohammad Hossein Ghahremani
- Applicant: Fatemeh Atyabi , Mohsen Adeli , Zahra Sobhani , Rassoul Dinarvand , Mohammad Hossein Ghahremani
- Main IPC: A61K9/51
- IPC: A61K9/51 ; C07B41/12 ; A61K9/00

Abstract:
A method for synthesizing carbon nanotube drug carriers and the carbon nanotube drug carriers are disclosed. Initially, carbon nanotubes, nitric acid, and sulfuric acid are mixed to oxidize carbon nanotubes in a first mixture. The oxidized carbon nanotubes are then extracted from the first mixture. The oxidized carbon nanotubes and monohydrated citric acid are mixed to synthesize carbon nanotubes grafted with poly(citric acid) in a second mixture. The carbon nanotubes grafted with poly(citric acid) are then extracted from the second mixture. The carbon nanotubes grafted with poly(citric acid) and 4-(dimethylamino)pyridine are dissolved in anhydrous dimethylformamide in a third mixture. Next, a mixture that comprises a drug is added to the third mixture to synthesize the carbon nanotubes grafted with poly(citric acid) and the drug in a fourth mixture. Then, the carbon nanotubes grafted with poly(citric acid) and the drug are extracted from the fourth mixture.
Public/Granted literature
- US20100324315A1 POLY(CITRIC ACID) FUNCTIONALIZED CARBON NANOTUBE DRUG DELIVERY SYSTEM Public/Granted day:2010-12-23
Information query