Invention Grant
- Patent Title: Targeting PAX2 for the treatment of breast cancer
- Patent Title (中): 针对PAX2治疗乳腺癌
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Application No.: US13114824Application Date: 2011-05-24
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Publication No.: US08461101B2Publication Date: 2013-06-11
- Inventor: Carlton D. Donald
- Applicant: Carlton D. Donald
- Applicant Address: US GA Atlanata
- Assignee: Phigenix, Inc.
- Current Assignee: Phigenix, Inc.
- Current Assignee Address: US GA Atlanata
- Agency: Andrews Kurth LLP
- Agent Ping Wang
- Main IPC: A61K31/00
- IPC: A61K31/00 ; C12N15/11 ; C12Q1/68
Abstract:
The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject.
Public/Granted literature
- US20110223162A1 TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER Public/Granted day:2011-09-15
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