Invention Grant
- Patent Title: Anthranilic acid derivatives
- Patent Title (中): 邻氨基苯甲酸衍生物
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Application No.: US13551290Application Date: 2012-07-17
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Publication No.: US08461205B2Publication Date: 2013-06-11
- Inventor: Helén Tuvesson Andersson , Ulf Vellmar , Ingrid Hallin , Leif Svenson , Ingela Fritzson
- Applicant: Helén Tuvesson Andersson , Ulf Vellmar , Ingrid Hallin , Leif Svenson , Ingela Fritzson
- Applicant Address: US NC Charlotte
- Assignee: Chelsea Therapeutics, Inc.
- Current Assignee: Chelsea Therapeutics, Inc.
- Current Assignee Address: US NC Charlotte
- Agency: Womble Carlyle Sandridge & Rice, LLP
- Priority: SE0700281 20070206
- Main IPC: A61K31/195
- IPC: A61K31/195

Abstract:
Compounds of formula (I) are provided, wherein X is CH═CH, CH2O wherein the oxygen atom is bound to ring B, or OCH2 wherein the oxygen atom is bound to ring A; Y is hydrogen, straight or branched C1-C6 alkyl or a pharmaceutically acceptable inorganic cation; R1 is ethyl or cyclopropyl; and R2 and R3 are the same or different and are selected from F, Cl, Br, CF3 and OCF3. The compounds are useful for the treatment of autoimmune diseases, inflammatory diseases, organ transplant rejection, and malignant neoplasia. Pharmaceutical compositions containing the compounds, methods of using the compounds, and methods for preparing the compounds are also provided.
Public/Granted literature
- US20120283326A1 ANTHRANILIC ACID DERIVATIVES Public/Granted day:2012-11-08
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