Invention Grant
US08461314B2 Nucleic acid sequences for biosynthesis of non-MccJ25-related lariat peptides
有权
用于非MccJ25相关梭菌肽生物合成的核酸序列
- Patent Title: Nucleic acid sequences for biosynthesis of non-MccJ25-related lariat peptides
- Patent Title (中): 用于非MccJ25相关梭菌肽生物合成的核酸序列
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Application No.: US12594152Application Date: 2007-09-20
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Publication No.: US08461314B2Publication Date: 2013-06-11
- Inventor: Richard H. Ebright , Konstantin Severinov
- Applicant: Richard H. Ebright , Konstantin Severinov
- Applicant Address: US NJ New Brunswick
- Assignee: Rutgers, The State University of New Jersey
- Current Assignee: Rutgers, The State University of New Jersey
- Current Assignee Address: US NJ New Brunswick
- Agency: Davidson, Davidson & Kappel, LLC
- International Application: PCT/US2007/079032 WO 20070920
- International Announcement: WO2008/121154 WO 20081009
- Main IPC: A61K38/12
- IPC: A61K38/12 ; C07H21/02 ; A61K38/00
Abstract:
A nucleic acid sequence is provided, encoding at least one of a precursor of a lariat peptide, a processing factor of a lariat peptide, and an export factor of a lariat peptide, wherein the lariat peptide is a non-MccJ25 lariat peptide according to general structural formula (I) Also provided are biosynthesis systems useful for the synthesis of peptides according to formula (I), and methods of detecting and identifying nucleic acid sequences encoding the disclosed proteins.
Public/Granted literature
- US20100261171A1 NUCLEIC ACID SEQUENCES FOR BIOSYNTHESIS OF NON-MCCJ25-RELATED LARIAT PEPTIDES Public/Granted day:2010-10-14
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