A liquid control apparatus controls movement of liquid in a microfluidic device having a sample introducing port, a sample delivering port, and a flow channel for holding liquid. The apparatus includes a vibration wave generating section for generating a vibration wave to be applied to the microfluidic device, and a signal supplying section for supplying drive signals so as to make the vibration wave generating section oscillate in different oscillation modes. The signal supplying section is capable of generating drive signals in a plurality of drive signal supply modes for realizing at least three of a transfer mode for moving liquid in a predetermined direction, a stop mode for stopping the movement of liquid, a mixing and/or agitation mode for mixing and/or agitating liquid, and a localization mode for localizing a predetermined substance in liquid, and for supplying the drive signals to the vibration wave generating section in a selected supply mode. In addition, the microfluidic device is held on the vibration wave generating section, and the transfer mode is carried out by using a resonance frequency to cause the microfluidic device to resonate.