The disclosure is related to systems and methods of dynamic dataflow in a multiple cache architecture. In an embodiment, a system having a data storage device with a multiple cache architecture may detect at least one attribute affecting a data storage workload or data storage performance. The system may select at least one of a plurality of data flow schemes based on the at least one attribute, which may be done to optimize the data storage workload for various conditions. In another embodiment, a data storage controller may automatically and dynamically select one of multiple data flow schemes within a data storage device having a multiple cache architecture. The data storage controller may monitor attributes to determine which data flow scheme to select for various workloads of the data storage device.