A system and method for Interference Cancellation (IC). One aspect relates to iterative interference cancellation with iterative finger delay adaptation. The interference cancellation method comprises receiving multi-paths of a signal; and performing iterative interference cancellation to remove multi-path interference, wherein the performing iterative IC comprises estimating a Signal-to-Interference-plus-Noise Ratio (SINR) at each of a plurality of pre-determined rake receiver finger delays, and performing successive Channel Estimation (CE) and IC on rake receiver fingers according to their estimated SINRs, and wherein the CE of a next finger does not start until interference of a previous finger is removed from a sample buffer. The method may further comprise improving estimated rake receiver finger delay, and each iteration decreases the amount of interference observed by each finger.