A self-sterilizing pass-through medications cabinet is built into a wall of a hospital room and can be accessed from the room interior or from the hallway. A frame mounted in the wall supports a rack or box containing patient drawers or bins, arranged in a vertical stack parallel to the wall or in a horizontal row. A hall-side door can be opened by pharmacy staff to place pre-loaded bins into respective compartments, and one or more room-side doors or drawers are opened by nurse staff for administering the medications to patients. The hallway door and room doors interlock to prevent their being opened at the same time to safeguard patient privacy. An ultraviolet germicidal illumination system bathes each bin in sterilizing radiation to destroy pathogens that may be present from handling or transport of the bins.