A medical plasma generator and its application are provided. In the medical plasma generator, a gas supply tube supplies a gas required for the generation of plasma. An internal electrode in a tube shape has a joined part joined to the end of the gas supply tube, and an extended part extended from the joined part. The extended part has a smaller diameter than the joined part, thereby allowing the gas to jet out with an increased speed when the gas passes through the internal electrode. A high voltage is applied to the internal electrode. A glass tube encloses the extended part of the internal electrode and protruding from the internal electrode. A ground electrode is formed on an outer surface of a protruding part of the glass tube. Interaction between the ground electrode and the internal electrode leads to ionization and discharge of the gas passing through the internal electrode, thereby generating plasma. A tubular cover covers the glass tube and is extended beyond the glass tube. The medical plasma generator may be used alone or in combination with medical equipment such as en endoscope.