Invention Grant
- Patent Title: Immunogenic reagents from west nile virus
- Patent Title (中): 西尼罗病毒的免疫原性试剂
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Application No.: US10557427Application Date: 2004-05-21
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Publication No.: US08475808B2Publication Date: 2013-07-02
- Inventor: William Andrews , David Chien , Qui-Lim Choo , Stephen Coates , Doris Coit , Charles Harrington , Susan Hilt , Michael Houghton , Angelica Medina-Selby , Sergio Pichuantes , Yiu-Lian Fong
- Applicant: William Andrews , David Chien , Qui-Lim Choo , Stephen Coates , Doris Coit , Charles Harrington , Susan Hilt , Michael Houghton , Angelica Medina-Selby , Sergio Pichuantes , Yiu-Lian Fong
- Applicant Address: US CA Emeryville
- Assignee: Novartis Vaccines and Diagnostics, Inc.
- Current Assignee: Novartis Vaccines and Diagnostics, Inc.
- Current Assignee Address: US CA Emeryville
- Agent Helen Lee; Roberta L. Robins
- International Application: PCT/US2004/015976 WO 20040521
- International Announcement: WO2004/112694 WO 20041229
- Main IPC: A61K39/12
- IPC: A61K39/12 ; C12Q1/70 ; C12N15/86

Abstract:
Recombinant production of immunogenic West Nile Virus (WNV) proteins is described. These proteins, heterodimers comprising the proteins, fusions thereof, polynucleotides encoding the proteins, and combinations thereof, as well as antibodies produced therefrom, can be used in immunogenic compositions for preventing, treating and diagnosing WNV infection. Also described are highly sensitive ELISA and strip immunoassay methods for detecting the presence of WNV in biological samples.
Public/Granted literature
- US20070092538A1 Immunogenic reagents from west nile virus Public/Granted day:2007-04-26
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