Invention Grant
- Patent Title: Botulinum neurotoxin a protein receptor and uses thereof
- Patent Title (中): 肉毒杆菌神经毒素蛋白受体及其用途
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Application No.: US12084074Application Date: 2006-10-30
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Publication No.: US08476024B2Publication Date: 2013-07-02
- Inventor: Stefan Mahrhold , Johannes Wilhelm Bigalke , Andreas Rummel , Thomas Binz
- Applicant: Stefan Mahrhold , Johannes Wilhelm Bigalke , Andreas Rummel , Thomas Binz
- Applicant Address: DE Hannover
- Assignee: Toxogen GmbH
- Current Assignee: Toxogen GmbH
- Current Assignee Address: DE Hannover
- Agency: Bozicevic, Field & Francis LLP
- Agent Carol L. Francis
- Priority: DE102005051789 20051028
- International Application: PCT/EP2006/010420 WO 20061030
- International Announcement: WO2007/048638 WO 20070503
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/567 ; A61K38/00 ; A61K39/00
Abstract:
The invention relates to an isolated polypeptide of the luminal domain of synaptic vesicle glycoprotein 2C of Homo sapiens wherein at least 70 percent of the amino acid sequence is identical to the amino acid sequence of the SV2C of Homo sapiens. The polypeptide binds the HC fragment of botulinum neurotoxin A provided that the polypeptide is not the synaptic vesicle glycoprotein 2C of Homo sapiens.
Public/Granted literature
- US20090252722A1 Botulinum Neurotoxin a Protein Receptor and Uses Thereof Public/Granted day:2009-10-08
Information query
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