Invention Grant
US08476083B1 Spectro-temporal optical encoding of information using a time-gated fluorescence resonance transfer (FRET)
有权
使用时间门控荧光共振转移（FRET）的信息的光谱时间光编码
- Patent Title: Spectro-temporal optical encoding of information using a time-gated fluorescence resonance transfer (FRET)
- Patent Title (中): 使用时间门控荧光共振转移（FRET）的信息的光谱时间光编码
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Application No.: US13475177Application Date: 2012-05-18
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Publication No.: US08476083B1Publication Date: 2013-07-02
- Inventor: W. Russ Algar , Niko Hildebrandt , Alan L Huston , Igor L. Medintz
- Applicant: W. Russ Algar , Niko Hildebrandt , Alan L Huston , Igor L. Medintz
- Applicant Address: US DC Washington
- Assignee: The United States of America, as represented by the Secretary of the Navy
- Current Assignee: The United States of America, as represented by the Secretary of the Navy
- Current Assignee Address: US DC Washington
- Agent Amy Ressing; Roy Roberts
- Main IPC: G01N33/551
- IPC: G01N33/551 ; G01N21/76 ; C09K11/06 ; G01N33/53 ; G01N21/64
Abstract:
Described herein is a time-gated, two-step FRET relay effective to provide temporal transference of a prompt FRET pathway, or provide spectro-temporal encoding analytical signals and other information. A FRET relay assembly includes a long lifetime FRET donor (for example, a lanthanide complex), a semiconductor quantum dot (QD) configured as an intermediate acceptor/donor in FRET, and a fluorescent dye configured as a terminal FRET acceptor, wherein the long lifetime FRET donor has an excited state lifetime of at least one microsecond and the QD and fluorescent dye each have excited state lifetimes of less than 100 nanoseconds.
Information query
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