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US08476234B2 Long-acting coagulation factors and methods of producing same 有权
长效凝血因子及其制备方法

Long-acting coagulation factors and methods of producing same
Abstract:
Polypeptides and polynucleotides encoding same comprising at least one carboxy-terminal peptide (CTP) of chorionic gonadotrophin attached to a carboxy terminus of a coagulation factor and not to an amino terminus are disclosed. Pharmaceutical compositions comprising the polypeptides and polynucleotides of the invention and methods of using same are also disclosed.
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