Invention Grant
US08476274B2 Biaryl spiroaminooxazoline analogues as Alpha2C adrenergic receptor modulators
失效
双芳基螺氨基恶唑啉类似物作为α2C肾上腺素能受体调节剂
- Patent Title: Biaryl spiroaminooxazoline analogues as Alpha2C adrenergic receptor modulators
- Patent Title (中): 双芳基螺氨基恶唑啉类似物作为α2C肾上腺素能受体调节剂
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Application No.: US13655176Application Date: 2012-10-18
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Publication No.: US08476274B2Publication Date: 2013-07-02
- Inventor: Kevin D. McCormick , Li Dong , Christopher W. Boyce , Manuel de Lera Ruiz , Salem Fevrier , Jie Wu , Junying Zheng , Younong Yu , Jianhua Chao , Walter S. Won , Ashwin U. Rao , Rongze Kuang , Pauline C. Ting , Xianhai Huang , Ning Shao , Anandan Palani , Michael Y. Berlin , Robert G. Aslanian
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Gerard M. Devlin; H. Eric Fischer
- Main IPC: A61K31/501
- IPC: A61K31/501 ; A61K31/497 ; A61K31/506 ; A61K31/4439 ; A61K31/427 ; A61K31/423 ; C07D235/02 ; C07D405/02 ; C07D409/02 ; C07D413/02 ; C07D263/52
Abstract:
In its many embodiments, the present invention provides a novel class of biaryl spiroaminooxazoline analogues as modulators of α2C adrenergic receptor agonists, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more conditions associated with the α2C adrenergic receptors using such compounds or pharmaceutical compositions.
Public/Granted literature
- US20130045914A1 BIARYL SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS Public/Granted day:2013-02-21
Information query
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