Invention Grant
US08476285B2 Purine-core inhibitors of HSP90 and their use in treating cancer
有权
HSP90的嘌呤核心抑制剂及其在治疗癌症中的应用
- Patent Title: Purine-core inhibitors of HSP90 and their use in treating cancer
- Patent Title (中): HSP90的嘌呤核心抑制剂及其在治疗癌症中的应用
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Application No.: US12494917Application Date: 2009-06-30
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Publication No.: US08476285B2Publication Date: 2013-07-02
- Inventor: Ashok C. Bajji , Se-Ho Kim , Benjamin Markovitz , Richard Trovato , Rajendra Tangallapally , Mark B. Anderson , Daniel Wettstein , Mark Shenderovich , John A. Vanecko
- Applicant: Ashok C. Bajji , Se-Ho Kim , Benjamin Markovitz , Richard Trovato , Rajendra Tangallapally , Mark B. Anderson , Daniel Wettstein , Mark Shenderovich , John A. Vanecko
- Applicant Address: US UT Salt Lake City
- Assignee: Myrexis, Inc.
- Current Assignee: Myrexis, Inc.
- Current Assignee Address: US UT Salt Lake City
- Agency: Stoel Rives LLP
- Agent Herbert L. Ley, III; Kelly A. Echols
- Main IPC: A61K31/52
- IPC: A61K31/52 ; C07D473/34 ; A61P35/00
Abstract:
The invention relates to compounds of Formulae I-III: and therapeutic uses thereof, wherein A is chosen from a substituted or unsubstituted aryl, heteroaryl, heterocyclic, or carbocyclic group; B is chosen from a substituted or unsubstituted piperidine, homopiperidine, piperazine, pyrrolidine or azetidine group; R1 is chosen from hydro, alkyl, aryl, heteroaryl, amino, or halo; and L1, L2, are as defined herein.
Public/Granted literature
- US20100016586A1 THERAPEUTIC COMPOUNDS AND THEIR USE IN CANCER Public/Granted day:2010-01-21
Information query
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