Invention Grant
- Patent Title: α-ketoamide derivatives useful endothelial lipase inhibitors
- Patent Title (中): α-酮酰胺衍生物可用于内皮脂肪酶抑制剂
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Application No.: US13245137Application Date: 2011-09-26
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Publication No.: US08476302B2Publication Date: 2013-07-02
- Inventor: Michael N. Greco , Margery A. Connelly , Shyamali Ghosh , Dennis J. Hlasta , Edward C. Lawson , Eric Strobel , Michele A. Weidner-Wells , Hong Ye
- Applicant: Michael N. Greco , Margery A. Connelly , Shyamali Ghosh , Dennis J. Hlasta , Edward C. Lawson , Eric Strobel , Michele A. Weidner-Wells , Hong Ye
- Applicant Address: BE
- Assignee: Janssen Pharmaceutica N.V.
- Current Assignee: Janssen Pharmaceutica N.V.
- Current Assignee Address: BE
- Agent Yuriy P. Stercho
- Main IPC: A61K31/4245
- IPC: A61K31/4245 ; A61K31/4439 ; A61K31/433 ; C07D285/12 ; C07D417/12 ; C07D271/107
Abstract:
The present invention is directed to α-ketoamide derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by endothelial lipase, for example, cardiovascular disorders.
Public/Granted literature
- US20120077847A1 ALPHA-KETOAMIDE DERIVATIVES USEFUL ENDOTHELIAL LIPASE INHIBITORS Public/Granted day:2012-03-29
Information query
