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US08476459B2 Process for the preparation of 4-sulfinyl-pyrazole derivatives 失效
4-亚磺酰基 - 吡唑衍生物的制备方法

  • Patent Title: Process for the preparation of 4-sulfinyl-pyrazole derivatives
  • Patent Title (中): 4-亚磺酰基 - 吡唑衍生物的制备方法
  • Application No.: US13504574
    Application Date: 2010-10-26
  • Publication No.: US08476459B2
    Publication Date: 2013-07-02
  • Inventor: Alexander KortePaul Hornung
  • Applicant: Alexander KortePaul Hornung
  • Applicant Address: DE Ludwigshafen
  • Assignee: BASF SE
  • Current Assignee: BASF SE
  • Current Assignee Address: DE Ludwigshafen
  • Agency: Brinks Hofer Gilson & Lione
  • Priority: EP09174558 20091030
  • International Application: PCT/EP2010/066162 WO 20101026
  • International Announcement: WO2011/051284 WO 20110505
  • Main IPC: C07D231/44
  • IPC: C07D231/44
Process for the preparation of 4-sulfinyl-pyrazole derivatives
Abstract:
The present invention relates to a novel process for the preparation of a compound of formula (I), wherein R1, R2, R3, R4 and R5 are each independently selected from hydrogen, halogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy, C1-C4-haloalkoxy, nitro, cyano, and pentafluorothio; R6 is C1-C4-alkyl, or C1-C4-haloalkyl; by oxidation of a compound of formula (II) with an oxidation agent selected from trifluoroperacetic acid and trichloroperacetic acid in the presence of a catalyst selected from hydroxides, oxides, sulfates, acetates or trifluoroacetates of lithium, magnesium, calcium, strontium, barium, titanium (IV), zinc (II) and manganese (II).
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