Disclosed are asymmetric styryl derivatives and an organic light emitting diode prepared using the same. More particularly, there are provided asymmetric styryl derivatives that can provide a blue organic light emitting diode with superior thermal stability, as well as improved luminous efficiency, improved brightness, and extended lifetime, by synthesizing a novel thermally stable compound with a styryl structure represented by Formula 1, and using the compound as a dopant in an organic light emitting layer (EML) of a multilayered organic light emitting diode, and an organic light emitting diode prepared by the same.