In accordance with the teachings of the present disclosure, systems and methods for aligning blind-mate connectors are provided. In one embodiment, a system comprises an avionics processing canister that is coupled to a mounting block. The avionics processing canister comprises a first portion of a first blind-mate connector, and a face plate with a surface that defines a pin-hole and a slot. The slot has a short dimension substantially equal to the diameter of the pin-hole and a long dimension perpendicular to the short dimension. The long dimension is longer than the short dimension. The system also comprises a first fastener that is received through the pin-hole and then into a first hole defined by a surface of the mounting block. The pin-hole has a diameter that is substantially equal to an outer diameter of the first fastener. The system also comprises a second fastener that is received through the slot and then into a second hole defined by a surface of the mounting block. The slot is oriented such that the second fastener constrains rotation of the face plate about a center of the pin-hole to align the first portion of the first blind-mate connector to a second portion of the first blind-mate connector.