A method and a device for processing data in a dedicated physical data channel, comprising, when data on which softer handover is performed is extended DPDCH data, sending, after completing the softer merging of the data for one timeslot, a request for secondary despread, where the request contains channel numbers; acquiring the request for secondary despread, determining channels according to the channel numbers contained in the request for secondary despread, determining a channel having the highest priority from the channels according to a predetermined channel priority order, and secondarily despreading, framing and outputting data of the channel having the highest priority. Due to the arrangement of the extended DPDCH, embodiments of this invention process the data carried by the extended DPDCH at the frequency of timeslots, and thus reduce the time delay of the second despreading and support services having higher requirements for logic processing delay without affecting the process for the existing normal DPDCH data.