A device for occluding septal defects or other bodily passageways includes two anchors connected to an occluding body. The occluding body may be formed as a plug or tube of biocompatible material configured to occlude a bodily passageway. At least one of the anchors includes a grasping member in the form of a loop or suitably shaped structure, which is configured for releasable attachment to an anchor engaging member, such as a biopsy forceps. In a further aspect a closure device assembly includes a closure device linked to the biopsy forceps and collapsibly disposed in a catheter. By positioning the catheter near a bodily passageway, such as a PFO, and disengaging the forceps from the grasping member, the closure device may be released so as to facilitate stable closure of a septal opening, such as a PFO.