Invention Grant
US08481042B2 Conjugates of pyrrolo[1,4]benzodiazepine dimers as anticancer agents
有权
吡咯并[1,4]苯并二氮杂二聚体作为抗癌剂的结合物
![Conjugates of pyrrolo[1,4]benzodiazepine dimers as anticancer agents](/docs/US/2013-07-09/US08481042B2/abs.jpg.600x600.jpg)
- Patent Title: Conjugates of pyrrolo[1,4]benzodiazepine dimers as anticancer agents
- Patent Title (中): 吡咯并[1,4]苯并二氮杂二聚体作为抗癌剂的结合物
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Application No.: US13404872Application Date: 2012-02-24
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Publication No.: US08481042B2Publication Date: 2013-07-09
- Inventor: Alain Commercon , Laurence Gauzy-Lazo
- Applicant: Alain Commercon , Laurence Gauzy-Lazo
- Applicant Address: FR Paris
- Assignee: Sanofi
- Current Assignee: Sanofi
- Current Assignee Address: FR Paris
- Agent Brian R. Morrill
- Priority: FR0904043 20090825; FR0904368 20090911
- Main IPC: A61K39/44
- IPC: A61K39/44 ; A61K38/00 ; A61K31/7088 ; A61K31/5517 ; A61P35/00 ; C07D487/04 ; C07H21/00 ; C07K14/00
![Conjugates of pyrrolo[1,4]benzodiazepine dimers as anticancer agents](/abs-image/US/2013/07/09/US08481042B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to pyrrolo[1,4]benzodiazepine (PBD) dimer conjugates, to the compositions comprising them and to their therapeutic application, in particular as anticancer agents. The invention also relates to the process for the preparation of the conjugates, to their application as anticancer agents and to the dimers themselves.
Public/Granted literature
- US20120244172A1 Conjudates of Pyrrolo[1,4]Benzodiazepine Dimers As Anticancer Agents Public/Granted day:2012-09-27
Information query
