Invention Grant
- Patent Title: PIK4CA as modifier of the Rac pathway and methods of use
- Patent Title (中): PIK4CA作为Rac途径的修饰剂和使用方法
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Application No.: US11575233Application Date: 2005-09-15
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Publication No.: US08481269B2Publication Date: 2013-07-09
- Inventor: Lisa C. Kadyk , George Ross Francis , Lynn Margaret Bjerke , Timothy S. Heuer
- Applicant: Lisa C. Kadyk , George Ross Francis , Lynn Margaret Bjerke , Timothy S. Heuer
- Applicant Address: US CA South San Francisco
- Assignee: Exelixis, Inc.
- Current Assignee: Exelixis, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- International Application: PCT/US2005/032838 WO 20050915
- International Announcement: WO2006/033942 WO 20060330
- Main IPC: C12Q1/34
- IPC: C12Q1/34
Abstract:
Human PIK4CA genes are identified as modulators of the RAC pathway, and thus are therapeutic targets for disorders associated with defective RAC function. Methods for identifying modulators of RAC, comprising screening for agents that modulate the activity of PIK4CA are provided.
Public/Granted literature
- US20080263684A1 Pik4ca As Modifier of the Rac Pathway and Methods of Use Public/Granted day:2008-10-23
Information query
