Invention Grant
- Patent Title: Method of detecting pancreatic cancer
- Patent Title (中): 检测胰腺癌的方法
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Application No.: US13509797Application Date: 2011-01-17
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Publication No.: US08481275B2Publication Date: 2013-07-09
- Inventor: Yuka Kobayashi , Ken Kusama , Masugu Kamei
- Applicant: Yuka Kobayashi , Ken Kusama , Masugu Kamei
- Applicant Address: JP Tokyo
- Assignee: J-Oil Mills, Inc.
- Current Assignee: J-Oil Mills, Inc.
- Current Assignee Address: JP Tokyo
- Priority: JP2010-011447 20100121
- International Application: PCT/JP2011/050621 WO 20110117
- International Announcement: WO2011/089988 WO 20110728
- Main IPC: G01N33/53
- IPC: G01N33/53
Abstract:
To provide a method of accurately detecting pathological haptoglobin using a lectin having strong affinity and high specificity for fucose. The method of the present invention for detecting pancreatic cancer is characterized in that a fucose α1→6 specific lectin is allowed to act on pathological haptoglobin contained in a sample obtained from a living body, said lectin: (1) being extractede from basidiomycetes, (2) having a molecular weight of 4,000 to 40,000 as determined by the SDS polyacrylamide gel electrophoresis, and (3) having affinity for a fucose α1→6 sugar chain with a binding constant of 1.0×104 M−1 or more at 25° C.
Public/Granted literature
- US20120244563A1 METHOD OF DETECTING PANCREATIC CANCER Public/Granted day:2012-09-27
Information query
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