- Patent Title: Ex vivo method for determining potential GLP-2 receptor modulators
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Application No.: US13565618Application Date: 2012-08-02
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Publication No.: US08481276B2Publication Date: 2013-07-09
- Inventor: Lidia L. Demchyshyn , Hong Wang
- Applicant: Lidia L. Demchyshyn , Hong Wang
- Applicant Address: US NJ Bedminster
- Assignee: NPS Pharmaceuticals, Inc.
- Current Assignee: NPS Pharmaceuticals, Inc.
- Current Assignee Address: US NJ Bedminster
- Agency: Stoel Rives LLP
- Main IPC: G01N33/567
- IPC: G01N33/567 ; A01N1/00 ; A01N1/02
Abstract:
Disclosed herein is a method for measuring the contractility of intestinal tissue upon treatment with GLP-2 or a GLP-2 ligand. Also disclosed is an assay which directly measures the activity of GLP-2 or GLP-2 ligands ex vivo and permits the screening of putative GLP-2 ligands in native tissue.
Public/Granted literature
- US20120295298A1 EX VIVO METHOD FOR DETERMINING POTENTIAL GLP-2 RECEPTOR MODULATORS Public/Granted day:2012-11-22
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