Invention Grant
US08481316B2 Method for differentiating embryonic stem cells into cells expressing AQP-1
有权
将胚胎干细胞分化成表达AQP-1的细胞的方法
- Patent Title: Method for differentiating embryonic stem cells into cells expressing AQP-1
- Patent Title (中): 将胚胎干细胞分化成表达AQP-1的细胞的方法
-
Application No.: US12669457Application Date: 2008-07-21
-
Publication No.: US08481316B2Publication Date: 2013-07-09
- Inventor: Karl M. Schumacher , Jackie Y. Ying , Annegret Schumacher , Karthikeyan Narayanan , Gunter Maubach
- Applicant: Karl M. Schumacher , Jackie Y. Ying , Annegret Schumacher , Karthikeyan Narayanan , Gunter Maubach
- Applicant Address: SG Singapore
- Assignee: Agency for Science, Technology and Research
- Current Assignee: Agency for Science, Technology and Research
- Current Assignee Address: SG Singapore
- Agency: Klarquist Sparkman, LLP
- International Application: PCT/SG2008/000263 WO 20080721
- International Announcement: WO2009/011663 WO 20090122
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/02 ; C12N5/071

Abstract:
The present invention relates to methods of differentiating a human embryonic stem (ES) cell into a cell, specifically a renal epithelial cell, expressing AQP-I. The methods disclosed comprise culturing human ES cells in a renal specific medium in the presence of an extracellular matrix molecule. The cells produced according to said method can be used to treat renal related disorders such as renal failure, nephrosis, Bright's disease and glomerulitis.
Public/Granted literature
- US20110070280A1 METHOD FOR DIFFERENTIATING EMBRYONIC STEM CELLS INTO CELLS EXPRESSING AQP-1 Public/Granted day:2011-03-24
Information query