Invention Grant
- Patent Title: Modified soluble FGF receptor Fc fusions method
- Patent Title (中): 改良的可溶性FGF受体Fc融合方法
-
Application No.: US13348297Application Date: 2012-01-11
-
Publication No.: US08481487B2Publication Date: 2013-07-09
- Inventor: Francis Blanche , Béatrice Cameron , Sylvie Sordello , Céline Nicolazzi , Marc Trombe , Mark Nesbit
- Applicant: Francis Blanche , Béatrice Cameron , Sylvie Sordello , Céline Nicolazzi , Marc Trombe , Mark Nesbit
- Applicant Address: FR Antony
- Assignee: Aventis Pharma S.A.
- Current Assignee: Aventis Pharma S.A.
- Current Assignee Address: FR Antony
- Agency: Lathrop & Gage LLP
- Agent James H. Velema
- Priority: EP06291824 20061128; EP07290042 20070111
- Main IPC: A61K38/18
- IPC: A61K38/18
Abstract:
The invention relates to modified soluble FGF receptor Fc fusions comprising a fusion of a soluble fragment or domain of the FGF receptor part (targeting or binding moiety) with an Fc region of an immunoglobulin part (effector function moiety), having improved biological activity including ADCC/CDC activities, compositions containing them, and method of producing such modified soluble FGF receptor Fc fusion molecules.
Public/Granted literature
- US20120195851A1 MODIFIED SOLUBLE FGF RECEPTOR FC FUSIONS WITH IMPROVED BIOLOGICAL ACTIVITY Public/Granted day:2012-08-02
Information query
IPC分类:
