Invention Grant
US08481499B2 Blockade of gamma-secretase activity to promote myelination by oligodendrocytes
有权
阻断γ-分泌酶活性以促进少突胶质细胞的髓鞘形成
- Patent Title: Blockade of gamma-secretase activity to promote myelination by oligodendrocytes
- Patent Title (中): 阻断γ-分泌酶活性以促进少突胶质细胞的髓鞘形成
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Application No.: US13066930Application Date: 2011-04-27
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Publication No.: US08481499B2Publication Date: 2013-07-09
- Inventor: Trent Alan Watkins , Ben A. Barres
- Applicant: Trent Alan Watkins , Ben A. Barres
- Applicant Address: US CA Palo Alto
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Palo Alto
- Agency: Bozicevic, Field & Francis LLP
- Agent Elizabeth A. Alcamo
- Main IPC: A61K38/55
- IPC: A61K38/55
Abstract:
Methods are provided for enhancing myelination. Myelination is enhanced by administration of agents that are inhibitors of γ-secretase. Methods of screening for pharmaceutically active compounds that enhance myelination, and for genes involved in myelination are also provided.
Public/Granted literature
- US20110251133A1 Blockade of gamma-secretase activity to promote myelination by oligodendrocytes Public/Granted day:2011-10-13
Information query
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