Invention Grant
US08481505B2 Compositions and methods for the diagnosis and therapy of BCL2-associated cancers
有权
用于诊断和治疗BCL2相关癌症的组合物和方法
- Patent Title: Compositions and methods for the diagnosis and therapy of BCL2-associated cancers
- Patent Title (中): 用于诊断和治疗BCL2相关癌症的组合物和方法
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Application No.: US11991773Application Date: 2006-09-11
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Publication No.: US08481505B2Publication Date: 2013-07-09
- Inventor: Carlo M. Croce , George A. Calin
- Applicant: Carlo M. Croce , George A. Calin
- Applicant Address: US OH Columbus
- Assignee: The Ohio State University Research Foundation
- Current Assignee: The Ohio State University Research Foundation
- Current Assignee Address: US OH Columbus
- Agency: MacMillan, Sobanski & Todd, LLC
- International Application: PCT/US2006/035100 WO 20060911
- International Announcement: WO2007/033023 WO 20070322
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C61K48/00 ; C07H21/02 ; C07H21/04
Abstract:
The invention provides methods and compositions for the treatment of cancers associated with overexpression of a BCL2 gene and/or gene product in a subject, and methods and compositions for the improvement of anti-cancer therapy, such as chemotherapy and radiation therapy. The invention also encompasses methods for determining the efficacy of a cancer therapy in a subject and methods for inducing apoptosis of a cell.
Public/Granted literature
- US20100184830A1 Compositions and Methods for the Diagnosis and Therapy of BCL2-Associated Cancers Public/Granted day:2010-07-22
Information query
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