Invention Grant
US08481515B2 Derivatives of cholest-4-en-3-one oxime, pharmaceutical compositions containing them and preparation method
有权
胆甾-4-烯-3-酮肟的衍生物,含有它们的药物组合物及其制备方法
- Patent Title: Derivatives of cholest-4-en-3-one oxime, pharmaceutical compositions containing them and preparation method
- Patent Title (中): 胆甾-4-烯-3-酮肟的衍生物,含有它们的药物组合物及其制备方法
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Application No.: US12158640Application Date: 2006-12-15
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Publication No.: US08481515B2Publication Date: 2013-07-09
- Inventor: Cyrille Drouot , Delphine Maux
- Applicant: Cyrille Drouot , Delphine Maux
- Applicant Address: FR Marseille
- Assignee: Trophos
- Current Assignee: Trophos
- Current Assignee Address: FR Marseille
- Agency: Browdy and Neimark, PLLC
- Priority: FR0512947 20051220
- International Application: PCT/FR2006/002740 WO 20061215
- International Announcement: WO2007/080270 WO 20070719
- Main IPC: A61K31/575
- IPC: A61K31/575 ; C07J41/00

Abstract:
The object of the invention is the use as a drug of a compound fitting formula I wherein X represents an oxygen atom or a ═N—OH group and R represents a group selected from or one of its esters and/or of its addition salts with pharmaceutically acceptable acids, particularly as a cytoprotective drug, preferentially a cardioprotective and/or neuroprotective drug, the compounds of formula I wherein R is R2, R3, R4, R5 or R6 as novel compounds as well as their preparation method and use.
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