Isolation of atraric acid, synthesis of atraric acid derivatives, and use of atraric acid and the derivatives thereof for the treatment of benign prostatic hyperplasia, prostate carcinoma and spinobulbar muscular atrophy

Invention Grant

US08481519B2 Isolation of atraric acid, synthesis of atraric acid derivatives, and use of atraric acid and the derivatives thereof for the treatment of benign prostatic hyperplasia, prostate carcinoma and spinobulbar muscular atrophy 失效

Title translation: 阿曲酸的分离，阿曲酸衍生物的合成，以及使用阿曲酸及其衍生物用于治疗良性前列腺增生，前列腺癌和旋转肌肉肌萎缩

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Patent Title: Isolation of atraric acid, synthesis of atraric acid derivatives, and use of atraric acid and the derivatives thereof for the treatment of benign prostatic hyperplasia, prostate carcinoma and spinobulbar muscular atrophy
Patent Title (中): 阿曲酸的分离，阿曲酸衍生物的合成，以及使用阿曲酸及其衍生物用于治疗良性前列腺增生，前列腺癌和旋转肌肉肌萎缩
Application No.: US11883610

Application Date: 2006-01-28
Publication No.: US08481519B2

Publication Date: 2013-07-09
Inventor: Hans-Rainer Hoffmann , Rudolf Matusch , Aria Baniahmad
Applicant: Hans-Rainer Hoffmann , Rudolf Matusch , Aria Baniahmad
Applicant Address: DE Andernach
Assignee: LTS Lohmann Therapie-Systeme AG
Current Assignee: LTS Lohmann Therapie-Systeme AG
Current Assignee Address: DE Andernach
Agent D. Peter Hochberg; Sean F. Mellino
Priority: DE102005005399 20050205
International Application: PCT/EP2006/000749 WO 20060128
International Announcement: WO2006/081997 WO 20060810
Main IPC: A01N43/00
IPC: A01N43/00 ; A61K31/33

Isolation of atraric acid, synthesis of atraric acid derivatives, and use of atraric acid and the derivatives thereof for the treatment of benign prostatic hyperplasia, prostate carcinoma and spinobulbar muscular atrophy

Abstract:

A method for isolating atraric acid from biological material, atraric acid derivatives, the chemical synthesis thereof, and the use of atraric acid and the derivatives thereof for treating or producing a medicament for treating benign prostate hyperplasia, prostate carcinoma or spinobulbar muscular atrophy is provided. In addition, a basic substance for the development of other agents used for treating benign prostate hyperplasia, prostate carcinoma, or spinobulbar muscular atrophy is provided.

Abstract(Chinese):

提供了从生物材料中分离过酸的方法，过敏酸衍生物，其化学合成，以及使用阿曲酸及其衍生物来治疗或产生治疗良性前列腺增生，前列腺癌或旋涡状肌肉萎缩的药物。另外，提供了用于治疗良性前列腺增生，前列腺癌或旋涡状肌肉萎缩的其它药物的开发的基本物质。

Public/Granted literature

US20090143466A1 Isolation of Atraric Acid, Synthesis of Atraric Acid Derivatives, and Use of Atraric Acid and the Derivatives Thereof for the Treatment of Benign Prostatic Hyperplasia, Prostate Carcinoma and Spinobulbar Muscular Atrophy Public/Granted day:2009-06-04

Information query

Espacenet

IPC分类:

A	人类生活必需
A01	农业；林业；畜牧业；狩猎；诱捕；捕鱼
A01N	人体、动植物体或其局部的保存（食品或粮食的保存入A23）；杀生剂，例如作为消毒剂，作为农药或作为除草剂（杀灭或防止不期望生物体的生长或繁殖的医用、牙科用或梳妆用的配制品入A61K）；害虫驱避剂或引诱剂；植物生长调节剂
A01N43/00	含有杂环化合物的杀生剂、害虫驱避剂或引诱剂，或植物生长调节剂（含有环酐，环状亚胺的化合物入A01N37/00；含有分子式Xm……CnNCC的化合物，即仅含1个杂环，其中m≥1和n≥0及NCC是未取代的或是烷基取代的吡咯烷、哌啶、吗啉、硫代吗啉、哌嗪或带有4个或更多CH2基的聚亚甲基亚胺的化合物入A01N33/00至A01N41/12；含环丙烷羧酸或其衍生物，如具有杂环的酯入A01N53/00）