Invention Grant
- Patent Title: Compositions and methods for inhibiting cytochrome P450
- Patent Title (中): 抑制细胞色素P450的组合物和方法
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Application No.: US13287079Application Date: 2011-11-01
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Publication No.: US08481520B2Publication Date: 2013-07-09
- Inventor: Michael Eissenstat , Dehui Duan
- Applicant: Michael Eissenstat , Dehui Duan
- Applicant Address: US MD Gaithersburg
- Assignee: Sequoia Pharmaceuticals, Inc.
- Current Assignee: Sequoia Pharmaceuticals, Inc.
- Current Assignee Address: US MD Gaithersburg
- Agency: Perkins Coie LLP
- Main IPC: A61K31/33
- IPC: A61K31/33
Abstract:
Methods of inhibiting cytochrome P450 enzymes are provided that can be used for improving the treatment of diseases by preventing degradation of drugs or other molecules by cytochrome P450. Pharmaceutical compositions are provided that can act as boosters to improve the pharmacokinetics, enhance the bioavailability, and enhance the therapeutic effect of drugs that undergo in vivo degradation by cytochrome P450 enzymes.
Public/Granted literature
- US20120053132A1 COMPOSITIONS AND METHODS FOR INHIBITING CYTOCHROME P450 Public/Granted day:2012-03-01
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