Invention Grant
- Patent Title: Crystalline forms and processes for the preparation of phenyl-pyrazoles useful as modulators of the 5-HT2A serotonin receptor
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Application No.: US12301212Application Date: 2007-05-17
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Publication No.: US08481535B2Publication Date: 2013-07-09
- Inventor: Tawfik Gharbaoui , Dipanjan Sengupta , Ashwin M. Krishnan , Nainesh Shah , Ryan M. Hart , Mark Macias , Edward A. Lally , Jonathan Duffield
- Applicant: Tawfik Gharbaoui , Dipanjan Sengupta , Ashwin M. Krishnan , Nainesh Shah , Ryan M. Hart , Mark Macias , Edward A. Lally , Jonathan Duffield
- Applicant Address: US CA San Diego
- Assignee: Arena Pharmaceuticals, Inc.
- Current Assignee: Arena Pharmaceuticals, Inc.
- Current Assignee Address: US CA San Diego
- International Application: PCT/US2007/011810 WO 20070517
- International Announcement: WO2007/136689 WO 20071129
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; A61K31/496 ; C07D295/185 ; C07D403/12

Abstract:
The present invention relates to processes for preparing phenyl-pyrazoles of Formula (I) and salts and pharmaceutical compositions thereof, useful as modulators of 5-HT2A serotonin receptor activity. The present invention also relates to intermediates used in the processes, and their preparation. The present invention also relates to crystalline forms of 5-HT2A serotonin receptor modulators, compositions thereof and methods of using the same.
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