Invention Grant
![3-(imidazolyl)-pyrazolo[3,4-b] pyridines](/docs/US/2013-07-09/US08481545B2/abs.jpg.600x600.jpg)
- Patent Title: 3-(imidazolyl)-pyrazolo[3,4-b] pyridines
- Patent Title (中): 3-（咪唑基） - 吡唑并[3,4-b]吡啶
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Application No.: US13103993Application Date: 2011-05-09
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Publication No.: US08481545B2Publication Date: 2013-07-09
- Inventor: Lianfa Li , Andrew M. K. Pennell , Penglie Zhang
- Applicant: Lianfa Li , Andrew M. K. Pennell , Penglie Zhang
- Applicant Address: US CA Mountain View
- Assignee: ChemoCentryx, Inc.
- Current Assignee: ChemoCentryx, Inc.
- Current Assignee Address: US CA Mountain View
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: A61K31/496
- IPC: A61K31/496 ; C07D487/04
![3-(imidazolyl)-pyrazolo[3,4-b] pyridines](/abs-image/US/2013/07/09/US08481545B2/abs.jpg.150x150.jpg)
Abstract:
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are 3-imidazoyl-pyrazolo[3,4-b]pyridine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated disease, and as controls in assays for the identification of competitive CCR1 antagonists.
Public/Granted literature
- US20120010214A1 3-(IMIDAZOLYL)-PYRAZOLO[3,4-b]PYRIDINES Public/Granted day:2012-01-12
Information query
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