Invention Grant
- Patent Title: Gyrase and topoisomerase IV inhibitors
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Application No.: US13349789Application Date: 2012-01-13
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Publication No.: US08481551B2Publication Date: 2013-07-09
- Inventor: Arnaud Le Tiran , Anne-Laure Grillot , Paul S. Charifson , Yousef Laafiret Bennani , Hardwin O'Dowd , Emanuele Perola
- Applicant: Arnaud Le Tiran , Anne-Laure Grillot , Paul S. Charifson , Yousef Laafiret Bennani , Hardwin O'Dowd , Emanuele Perola
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agency: Brinks Hofer Gilson & Lione
- Agent William R. Boudreaux; Joshua E. Ney
- Main IPC: A01N43/54
- IPC: A01N43/54 ; C07D239/42 ; C07D471/04
Abstract:
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The compounds of formula (I) are useful as gyrase and/or topoisomerase IV inhibitors for treating bacterial infections. The compounds of formula (I) either possess a broad range of anti-bacterial activity and advantageous toxicological properties or are prodrugs of compounds having said activity.
Public/Granted literature
- US20120184512A1 GYRASE AND TOPOISOMERASE IV INHIBITORS Public/Granted day:2012-07-19
Information query
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