Invention Grant
- Patent Title: Modulators of sphingosine phosphate receptors
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Application No.: US13605561Application Date: 2012-09-06
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Publication No.: US08481573B2Publication Date: 2013-07-09
- Inventor: Edward Roberts , Hugh Rosen , Steven Brown , Miguel A. Guerrero , Xuemei Peng , Ramulu Poddutoori
- Applicant: Edward Roberts , Hugh Rosen , Steven Brown , Miguel A. Guerrero , Xuemei Peng , Ramulu Poddutoori
- Applicant Address: US CA La Jolla
- Assignee: The Scripps Research Institute
- Current Assignee: The Scripps Research Institute
- Current Assignee Address: US CA La Jolla
- Agency: Schwegman Lundberg & Woessner, P.A.
- Main IPC: A61K31/4245
- IPC: A61K31/4245 ; C07D271/06
Abstract:
Compounds of the following generic structure are provided: Such compounds activate a sphingosine-I-phosphate receptor of the subtype 1 (S1P1), and have utility in the treatment of malconditions mediated by S1P1 activation. More specifically, such compounds are beneficial in the treatment of, for example, multiple sclerosis, transplant rejection and/or adult respiratory syndrome.
Public/Granted literature
- US20120329840A1 NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS Public/Granted day:2012-12-27
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