Invention Grant
US08481576B2 Guanidine compounds, and use thereof as binding partners for 5-HT5 receptors
有权
胍化合物及其作为5-HT 5受体的结合伴侣的用途
- Patent Title: Guanidine compounds, and use thereof as binding partners for 5-HT5 receptors
- Patent Title (中): 胍化合物及其作为5-HT 5受体的结合伴侣的用途
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Application No.: US13021336Application Date: 2011-02-04
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Publication No.: US08481576B2Publication Date: 2013-07-09
- Inventor: Astrid Netz , Wilhelm Amberg , Udo Lange , Michael Ochse , Charles W. Hutchins , Francisco-Xavier Garcia-Ladona , Wolfgang Wernet , Andreas Kling
- Applicant: Astrid Netz , Wilhelm Amberg , Udo Lange , Michael Ochse , Charles W. Hutchins , Francisco-Xavier Garcia-Ladona , Andreas Kling , Andrea Hager-Wernet
- Applicant Address: DE Wiesbaden
- Assignee: Abbott GmbH & Co. KG
- Current Assignee: Abbott GmbH & Co. KG
- Current Assignee Address: DE Wiesbaden
- Agency: Michael Best & Friedrich LLP
- Agent Lisa V. Mueller
- Priority: DE102004008141 20040219
- Main IPC: A61K31/4184
- IPC: A61K31/4184 ; C07D213/24
Abstract:
The present invention relates to guanidine compounds of the general formula I corresponding enantiomeric, diastereomeric and/or tautomeric forms thereof as well as pharmaceutically acceptable salts thereof. The present compound further relates to the use of guanidine compounds as binding partners for 5-HT5 receptors for the treatment of diseases which are modulated by a 5-HT5 receptor activity, in particular for the treatment of neurodegenerative and neuropsychiatric disorders as well as the associated signs, symptoms and dysfunctions.
Public/Granted literature
- US20110237589A1 GUANIDINE COMPOUNDS, AND USE THEREOF AS BINDING PARTNERS FOR 5-HT5 RECEPTORS Public/Granted day:2011-09-29
Information query
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